Matrix Search - Test Information
Investigation | T. Transglutaminase (IgA TTG) | Indications | A screening test to detect for autoimmune antibodies from intolerance to gluten which suggestss coeliac disease. | Specimen Type | Ochre/Yellow top | Request Form | Blood Sciences or Electronic | Volume | Fill to line | Delivery Time | Within 24hrs | Turn around time for final test | 1 week when negative if positive upto 2 weeks | Uncertainty of testing | Patients need to maintain a gluten containing diet - present in at least 2 meals a day for 6 weeks prior to the test. The screening test will detect IgA deficiency, in these cases IgG TTG will be tested. | Reference range | negative or if quatified 6.9iu/mL if Pos 14.0iu/mL | Action limits | If low clinical suspicion positive results need GI biopsy. | Appropriate testing /re-testing interval | Minimum repeat time is 12 months in high risk patients. There is no need to retest known coeliac disease patients to assess diet compliance. | Related tests | None | HOW TO guides | None | Information leaflets | None | Publications | None | Guidelines | None |
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