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| Investigation | Carbapenemase Producing Enterobacteriaceae | | Indications | Carbapenems (imipenem, meropenem and ertapenem) have the most consistent activity of any antibiotics against
Enterobacteriaceae. Unlike 3rd and 4th generation cephalosporins, they are not inactivated by AmpC or extended-spectrum
ß-lactamases.
Carbapenemase-resistance is emerging in ESBL-producing Enterobacteriaceae, especially Klebsiella spp.
and Enterobacter spp.
· Resistance involves permeability/efflux changes along with the ESBL.
· Ertapenem is more affected than other carbapenems. | | Request Form | Microbiology | | Related tests | None | | HOW TO guides | None | | Information leaflets | None | | Publications | None | | Guidelines | None |
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