Matrix Search - Test Information
| Investigation | Carbapenemase Producers | | Indications | Carbapenems (imipenem, meropenem and ertapenem) have the most consistent activity of any antibiotics against Enterobacteriaceae.
Unlike 3rd and 4th generation cephalosporins, they are not inactivated by AmpC or extended-spectrum ß-lactamases.
Carbapenem-resistance is emerging in ESBL-producing Enterobacteriaceae, especially Klebsiella spp and Enterobacter spp.
· Resistance involves permeability/efflux changes along with the ESBL.
· Ertapenem is more affected than other carbapenems. | | Related tests | None | | HOW TO guides | None | | Information leaflets | None | | Publications | None | | Guidelines | None |
|
|